FERMENTERS/ BIOREACTORS by Bioengineering AG, Switzerland

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  • General
  • Technical details

KLF: In situ sterilizable small benchtop glass reactor

KLF is an in-situ sterilisable bench-top bioreactor made of glass. Since this is an in-situ bioreactor it is sterilized using electrical heating. It occupies less space compared to any conventional in-situ bioreactor. Ideal for scale-up and scale-down studies due to matched system design.
  • Working Volume: 1.6 / 2.0 / 2.5 liters
  • Vessel: Glass or stainless steel
  • Drive: Bottom drive with axial face seal or magnetic clutch
  • Stirrers: Rushton, propeller stirrers, pitched-blade stirrers
  • Aeration: Tube, ring sparger, sinter sparger, bubble-free gassing
  • Temperature control: Electrical heating & cooling fingers
  • Measurement and control technology: Agitation, temperature, pH, pO2, foam/level control, redox, OD, weight, exhaust analysis, numerous interfaces and regulators
  • Gas modules: Up to 6 individual gassing lines with pulsed valves or mass-flow controllers
  • Pump modules: Up to 6 pumps integrated in the control unit and one external pump
  • BioSCADA: Sophisticated control and visualization software including data collection
  • Configuration: Up to 6 bioreactors controllable with a single control unit
Specification and Configuration
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  • General
  • Technical details

RALF: Autoclavable, small bench-top glass reactor

RALF is an Autoclavable glass bioreactor with compact and modular design which makes it ideal for scale-up and scale-down studies.
 
  • Working volume: 1.3 / 2.5 / 3.3 / 4.5 liters
  • Vessel: Single or double-walled glass vessels
  • Drive: Direct top drive with axial face seal or magnetic clutch
  • Stirrers: Rushton, propeller stirrers, pitched-blade stirrers
  • Aeration: Tube, ring sparger, sinter sparger, bubble-free gassing
  • Temperature control: Heating pad and cooling fingers, heating circuit via perfused baffles, heating circuit via double wall of vessel
  • Measurement and control technology: Agitation, temperature, pH, pO2, foam/level control, redox, OD, weight, exhaust analysis, numerous interfaces and regulators
  • Gas modules: Up to 6 individual gassing lines with pulsed valves or mass-flow controllers
  • Pump modules: Up to 6 pumps integrated in the control unit and one external pump
  • BioSCADA: Sophisticated control and visualization software including data collection
  • Configuration: Up to 6 bioreactors controllable with a single control unit
Specification and Configuration
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  • General
  • Technical details

NLF: An extremely reliable and space saving bioreactor for small production volumes

The NLF is a bioreactor for small production volumes. The mobile unit is extremely reliable and space saving and is designed similar to production fermenters. Consequently it can be used for low-budget or high-budget production quantities. The system design makes it ideal for scale-up and scale-down studies. Can be equipped as a laboratory fermenter in manual operation, or as a seed reactor for a production fermenter.
  • Working Volume: 11 / 13 / 20 liters
  • Vessel: Stainless steel, double shell, double floor
  • Drives: Top drive, bottom drive, Vibromixer
  • Stirrers: Rushton, propeller stirrers, pitched-blade stirrers
  • Aeration: Tube, ring sparger, sinter sparger, bubble-free gassing
  • Temperature control: Electrical heating & cooling fingers
  • Measurement and control technology: Agitation, temperature, pH, pO2, foam/level control, redox, OD, weight, exhaust analysis, numerous interfaces and regulators
  • Gas modules: Up to 6 individual gassing lines with pulsed valves or mass-flow controllers
  • Pump modules: Up to 6 pumps
  • Cleaning:  Manually / CIP
  • BioSCADA: Sophisticated control and visualization software including data collection
  • Configuration: Up to 6 bioreactors controllable with a single control unit
Specification and Configuration
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  • General
  • Technical details

LP/P: Laboratory Pilot- In small bioprocess labs, this model can be used as pilot scale reactor

The LP and P bioreactor series is based on the same platform concept as NLF, only bigger. These bioreactors and fermenters are very easily scalable. These are hi-tech bioreactors for bacteria, yeasts, animal and plant cells.
Can be equipped as a laboratory fermenter in manual operation, or as a seed reactor for a production fermenter.
  • Working Volume: 28 / 33 / 50 / 65 / 100 / 130 / 200 / 300 / 500 / 650 liters
  • Vessel: Stainless steel, double shell, double floor
  • Drives: Bottom drive with belt, double axial face seal, magnetic drive, top drive
  • Stirrers: Rushton, propeller stirrers, pitched-blade stirrers, Vibromixer
  • Gassing: Auto-sterile filters, separate filters or double filters. Ring sparger, sinter sparger, surface gassing, bubble-free gassing. Up to 8 gassing lines with pulsed valves or mass-flow controllers.
  • Temperature circuit and sterilization: Steam heating / Cooling water. Automated sterilization, empty sterilization.
  • Measurement and control technology: Speed, temperature, pH, pO2, antifoam/level, redox, OD, weight, exhaust-gas analysis. Several interfaces and regulators available for external devices/equipment. 
  • Dosing /Transfer: Manual dosing, SteriCaps, transfer concepts, full valve automation. Up to 6 pump module selectable. 
  • BioSCADA: Sophisticated control and visualization software including data collection