FERMENTERS/ BIOREACTORS by Bioengineering AG, Switzerland

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  • General
  • Technical details

KLF: In situ sterilizable small benchtop glass reactor

KLF is an in-situ sterilisable bench-top bioreactor made of glass. Since this is an in-situ bioreactor it is sterilized using electrical heating. It occupies less space compared to any conventional in-situ bioreactor. Ideal for scale-up and scale-down studies due to matched system design.

 
 
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  • Working Volume: 1.6 / 2.0 / 2.5 liters

  • Vessel: Glass or stainless steel

  • Drive: Bottom drive with axial face seal or magnetic clutch

  • Stirrers: Rushton, propeller stirrers, pitched-blade stirrers

  • Aeration: Tube, ring sparger, sinter sparger, bubble-free gassing

  • Temperature control: Electrical heating & cooling fingers

  • Measurement and control technology: Agitation, temperature, pH, pO2, foam/level control, redox, OD, weight, exhaust analysis, numerous interfaces and regulators

  • Gas modules: Up to 6 individual gassing lines with pulsed valves or mass-flow controllers

  • Pump modules: Up to 6 pumps integrated in the control unit and one external pump

  • BioSCADA: Sophisticated control and visualization software including data collection

  • Configuration: Up to 6 bioreactors controllable with a single control unit

Specification and Configuration

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  • General
  • Technical details

RALF: Autoclavable, small bench-top glass reactor

RALF is an Autoclavable glass bioreactor with compact and modular design which makes it ideal for scale-up and scale-down studies.

 
 
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  • Working volume: 1.3 / 2.5 / 3.3 / 4.5 liters

  • Vessel: Single or double-walled glass vessels

  • Drive: Direct top drive with axial face seal or magnetic clutch

  • Stirrers: Rushton, propeller stirrers, pitched-blade stirrers

  • Aeration: Tube, ring sparger, sinter sparger, bubble-free gassing

  • Temperature control: Heating pad and cooling fingers, heating circuit via perfused baffles, heating circuit via double wall of vessel

  • Measurement and control technology: Agitation, temperature, pH, pO2, foam/level control, redox, OD, weight, exhaust analysis, numerous interfaces and regulators

  • Gas modules: Up to 6 individual gassing lines with pulsed valves or mass-flow controllers

  • Pump modules: Up to 6 pumps integrated in the control unit and one external pump

  • BioSCADA: Sophisticated control and visualization software including data collection

  • Configuration: Up to 6 bioreactors controllable with a single control unit

Specification and Configuration

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  • General
  • Technical details

NLF: An extremely reliable and space saving bioreactor for small production volumes

The NLF is a bioreactor for small production volumes. The mobile unit is extremely reliable and space saving and is designed similar to production fermenters. Consequently it can be used for low-budget or high-budget production quantities. The system design makes it ideal for scale-up and scale-down studies. Can be equipped as a laboratory fermenter in manual operation, or as a seed reactor for a production fermenter.

 
 
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  • Working Volume: 11 / 13 / 20 liters

  • Vessel: Stainless steel, double shell, double floor

  • Drives: Top drive, bottom drive, Vibromixer

  • Stirrers: Rushton, propeller stirrers, pitched-blade stirrers

  • Aeration: Tube, ring sparger, sinter sparger, bubble-free gassing

  • Temperature control: Electrical heating & cooling fingers

  • Measurement and control technology: Agitation, temperature, pH, pO2, foam/level control, redox, OD, weight, exhaust analysis, numerous interfaces and regulators

  • Gas modules: Up to 6 individual gassing lines with pulsed valves or mass-flow controllers

  • Pump modules: Up to 6 pumps

  • Cleaning:  Manually / CIP

  • BioSCADA: Sophisticated control and visualization software including data collection

  • Configuration: Up to 6 bioreactors controllable with a single control unit

Specification and Configuration

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  • General
  • Technical details

LP/P: Laboratory Pilot- In small bioprocess labs, this model can be used as pilot scale reactor

The LP and P bioreactor series is based on the same platform concept as NLF, only bigger. These bioreactors and fermenters are very easily scalable. These are hi-tech bioreactors for bacteria, yeasts, animal and plant cells.

Can be equipped as a laboratory fermenter in manual operation, or as a seed reactor for a production fermenter.

 
 
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  • Working Volume: 28 / 33 / 50 / 65 / 100 / 130 / 200 / 300 / 500 / 650 liters

  • Vessel: Stainless steel, double shell, double floor

  • Drives: Bottom drive with belt, double axial face seal, magnetic drive, top drive

  • Stirrers: Rushton, propeller stirrers, pitched-blade stirrers, Vibromixer

  • Gassing: Auto-sterile filters, separate filters or double filters. Ring sparger, sinter sparger, surface gassing, bubble-free gassing. Up to 8 gassing lines with pulsed valves or mass-flow controllers.

  • Temperature circuit and sterilization: Steam heating / Cooling water. Automated sterilization, empty sterilization.

  • Measurement and control technology: Speed, temperature, pH, pO2, antifoam/level, redox, OD, weight, exhaust-gas analysis. Several interfaces and regulators available for external devices/equipment. 

  • Dosing /Transfer: Manual dosing, SteriCaps, transfer concepts, full valve automation. Up to 6 pump module selectable. 

  • BioSCADA: Sophisticated control and visualization software including data collection